Introduction
Advil is a nonsteroidal anti-inflammatory drug composed mainly of ibuprofen. It is used to relieve pain and lessen inflammation in joints, muscles, and fibrous tissue. As an athlete, I need to compete at the top of my game at all times, thus I cannot let pain slow me down. So I often find myself using advil and other painkillers to help me excel, and now I know what I am putting into my body and what it is doing.
Main Chemicals, Compounds, Components
Chemistry's Role
Pain is caused when prostaglandins produce too many white blood cells at an injured area. The ibuprofen in Advil reduces the activity in the enzyme cyclooxygenase, which synthesizes the prostaglandins, resulting in less white blood cells, which reduces swelling and pain.
Background Research
Ibuprofen was discovered in 1961 by Stewart Adams when it was derived from propionic acid, and originally called Brufen. Adams found it while working with a group who was set out to find a safer alternative for aspirin. Adams first tested it to see if it could cure his hangover, before launching it as a treatment for rheumatoid arthritis. It was first sold in 1969 in the UK and then in 1974 in the US. When it first came to the US it was sold by the name Advil.
Resources
About the Author
Nolan Askelson is a junior at Billings Senior High School. He enjoys watching and playing all sports. He was a starter on the state champion Senior football team. He also plays baseball for the Emmanuel Baptist Church Halos. He enjoys learning in school, but is especially fond of math.